Calcium D-glucarate is the calcium salt of D-glucarate, a compound made in the body through the oxidation of glucose. D-glucarate is also found naturally in grapefruit, apples, oranges and cruciferous vegetables.1,2 D-glucarate can be converted into another compound that helps the body clear steroid hormones and various toxins through a detoxification process called glucoronidation.
This active D-glucarate metabolite works by inhibiting an enzyme that reverses glucoronidation. By supporting effective detoxification, D-glucarate helps maintain optimal hormone levels and promote clearance.1-3 It also encourages a healthy inflammatory response and offers antioxidant protection.4-6
Calcium D-glucarate has been shown to support normal cell division in laboratory studies.7-9 In addition, D-glucarate has been found to help maintain already-healthy levels of cholesterol and other lipids.2